:root {
  --ink: #102b35;
  --muted: #49656b;
  --paper: #f3f7f5;
  --line: #ccd9d6;
  --teal: #087d7a;
  --wash: #e3efea;
  --amber: #9b570c;
  --white: #fff;
  font-family:
    Segoe UI,
    Arial,
    sans-serif;
  color: var(--ink);
  background: var(--paper);
  font-size: 17px;
  line-height: 1.7;
  color-scheme: light;
}
:root[data-theme="contrast"] {
  --ink: #eaf7f5;
  --muted: #b9cfcb;
  --paper: #071a20;
  --line: #31515a;
  --teal: #63dfcf;
  --wash: #12333a;
  --amber: #ffbf69;
  --white: #0d262d;
  color-scheme: dark;
}
* {
  box-sizing: border-box;
}
body {
  margin: 0;
}
a {
  color: var(--teal);
  text-underline-offset: 4px;
}
a:focus-visible,
button:focus-visible,
summary:focus-visible,
input:focus-visible {
  outline: 3px solid #b56b19;
  outline-offset: 4px;
}
button,
input {
  font: inherit;
}
button,
summary {
  cursor: pointer;
}
a.skip {
  position: absolute;
  top: -100px;
  left: 16px;
  background: white;
  padding: 12px;
  z-index: 50;
}
a.skip:focus {
  top: 10px;
}
.topbar {
  position: sticky;
  top: 0;
  z-index: 20;
  background: #102b35;
  color: white;
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 20px;
  padding: 14px max(20px, calc((100vw - 1280px) / 2));
  font-size: 0.76rem;
}
.brand {
  color: white;
  text-decoration: none;
  white-space: nowrap;
  letter-spacing: 0.05em;
}
.brand b {
  color: #50d3bd;
}
.topbar nav {
  display: flex;
  gap: 8px;
  overflow-x: auto;
  scrollbar-width: none;
  min-width: 0;
  max-width: 100%;
}
.topbar nav::-webkit-scrollbar {
  display: none;
}
.topbar nav a {
  white-space: nowrap;
  border: 1px solid #385159;
  color: #e1efeb;
  border-radius: 30px;
  text-decoration: none;
  padding: 6px 12px;
}
.topbar nav a[aria-current="location"] {
  background: #e1efeb;
  color: #102b35;
  border-color: #e1efeb;
}
.top-actions {
  display: flex;
  gap: 8px;
}
.print,
.theme {
  background: transparent;
  color: white;
  border: 1px solid #647c80;
  border-radius: 4px;
  padding: 6px 12px;
  white-space: nowrap;
  min-height: 40px;
}
.theme[aria-pressed="true"] {
  background: #e1efeb;
  color: #102b35;
}
.reading-progress {
  position: fixed;
  z-index: 40;
  top: 0;
  left: 0;
  width: 100%;
  height: 4px;
  background: transparent;
}
.reading-progress span {
  display: block;
  width: 100%;
  height: 100%;
  background: #50d3bd;
  transform: scaleX(0);
  transform-origin: left center;
}
main,
footer {
  max-width: 1280px;
  margin: auto;
  padding: 0 30px;
}
.hero {
  padding: 80px 0 48px;
}
.eyebrow {
  color: var(--teal);
  font-weight: 800;
  font-size: 0.72rem;
  letter-spacing: 0.14em;
  text-transform: uppercase;
}
.hero h1 {
  font-size: clamp(3.2rem, 7vw, 6.5rem);
  letter-spacing: -0.065em;
  line-height: 1.02;
  margin: 18px 0 28px;
  max-width: 1000px;
}
.hero h1 em {
  font-style: normal;
  color: var(--teal);
}
.lead {
  font-size: 1.18rem;
  color: var(--muted);
  max-width: 800px;
}
.meta {
  font-size: 0.82rem;
  color: var(--muted);
}
.actions {
  display: flex;
  gap: 12px;
  flex-wrap: wrap;
  margin: 24px 0;
}
.button {
  display: inline-block;
  background: var(--ink);
  color: white;
  text-decoration: none;
  padding: 12px 20px;
  border: 0;
  border-radius: 4px;
  font-weight: 700;
}
.button.secondary {
  background: var(--wash);
  color: var(--ink);
}
figure {
  margin: 28px 0;
  border: 1px solid var(--line);
  background: var(--white);
}
figure img {
  display: block;
  width: 100%;
  height: auto;
  max-width: 100%;
}
figure a {
  display: block;
}
figcaption {
  font-size: 0.82rem;
  color: var(--muted);
  padding: 12px 18px;
  line-height: 1.5;
}
.cover img {
  aspect-ratio: 3/2;
  object-fit: cover;
}
.chapter-visual {
  max-width: 1080px;
}
.chapter-visual img {
  aspect-ratio: 3/2;
  object-fit: cover;
}
.chapter-visual.device-photo img {
  background: var(--wash);
  object-fit: contain;
}
.chapter {
  padding: 44px 0 56px;
  border-top: 1px solid var(--line);
  scroll-margin-top: 90px;
}
.chapter-heading {
  display: grid;
  grid-template-columns: 52px 1fr;
  gap: 16px;
  margin-bottom: 26px;
}
.number {
  color: var(--teal);
  font-size: 0.82rem;
  font-weight: 800;
  padding-top: 10px;
}
h2 {
  font-size: clamp(1.9rem, 4vw, 3.6rem);
  line-height: 1.1;
  letter-spacing: -0.05em;
  margin: 0 0 12px;
}
h3 {
  font-size: 1.35rem;
  line-height: 1.3;
  margin: 30px 0 12px;
}
p {
  max-width: 90ch;
  margin: 14px 0;
}
li {
  margin: 8px 0;
}
ul,
ol {
  padding-left: 24px;
}
.note {
  padding: 20px 24px;
  background: var(--wash);
  border-left: 4px solid var(--teal);
  margin: 24px 0;
}
.warning {
  background: #fff3dd;
  border-color: var(--amber);
  color: #54380f;
}
.pediatric {
  background: #e7f0f8;
  border-color: #326480;
}
.grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 28px;
}
.grid > div {
  min-width: 0;
}
.grid h3 {
  margin-top: 8px;
}
.tag {
  display: inline-block;
  font-size: 0.7rem;
  font-weight: 800;
  text-transform: uppercase;
  letter-spacing: 0.08em;
  color: #165e66;
  border-bottom: 2px solid #70b8ad;
  margin-bottom: 6px;
}
.fio2-card {
  display: grid;
  grid-template-columns: minmax(140px, 0.32fr) minmax(0, 1fr);
  gap: 18px;
  align-items: center;
  max-width: 900px;
  margin: 14px 0 24px;
  padding: 16px 18px;
  border: 1px solid var(--line);
  border-left: 4px solid var(--teal);
  background: var(--white);
}
.fio2-card p {
  margin: 0;
  font-size: 0.9rem;
  line-height: 1.55;
}
.fio2-kicker {
  display: block;
  color: var(--muted);
  font-size: 0.68rem;
  font-weight: 800;
  letter-spacing: 0.08em;
  line-height: 1.3;
  text-transform: uppercase;
}
.fio2-value {
  display: block;
  color: var(--teal);
  font-size: clamp(1.25rem, 2.5vw, 1.85rem);
  line-height: 1.15;
  margin-top: 4px;
}
.fio2-grid {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 14px;
  max-width: 980px;
  margin: 14px 0 24px;
}
.fio2-grid .fio2-card {
  display: block;
  margin: 0;
}
.fio2-grid .fio2-card p {
  margin-top: 8px;
}
.reference {
  font-size: 0.8rem;
  color: var(--muted);
}
.reference a {
  margin-right: 12px;
}
.index {
  background: var(--wash);
  padding: 24px 30px;
  margin: 0 0 50px;
  scroll-margin-top: 90px;
}
.index summary {
  font-weight: 800;
  font-size: 1.1rem;
}
.index-search {
  display: grid;
  grid-template-columns: auto minmax(220px, 460px);
  align-items: center;
  gap: 16px;
  margin: 22px 0 4px;
  font-size: 0.8rem;
  font-weight: 800;
}
.index-search input {
  width: 100%;
  min-height: 44px;
  border: 1px solid var(--line);
  border-radius: 4px;
  background: var(--white);
  color: var(--ink);
  padding: 8px 12px;
}
.search-status {
  font-size: 0.76rem;
  color: var(--muted);
  margin: 4px 0 12px;
}
.index ol {
  columns: 3;
  column-gap: 40px;
  font-size: 0.85rem;
}
.index li {
  break-inside: avoid;
  padding: 3px;
}
.index li[hidden] {
  display: none;
}
.index a {
  text-decoration: none;
}
.table-wrap {
  overflow-x: auto;
  max-width: 100%;
  margin: 24px 0;
}
table {
  border-collapse: collapse;
  width: 100%;
  min-width: 620px;
  font-size: 0.9rem;
}
th,
td {
  padding: 14px;
  border: 1px solid var(--line);
  text-align: left;
  vertical-align: top;
}
thead th {
  background: #102b35;
  color: white;
}
tbody th {
  background: var(--wash);
}
tbody td {
  background: var(--white);
}
.checklist {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: 12px;
  margin: 24px 0;
}
.checklist label {
  display: flex;
  align-items: flex-start;
  gap: 10px;
  padding: 14px;
  background: var(--white);
  border: 1px solid var(--line);
  cursor: pointer;
}
.checklist input {
  width: 21px;
  height: 21px;
  flex-shrink: 0;
  accent-color: var(--teal);
  margin-top: 4px;
}
.case {
  margin: 16px 0;
  border: 1px solid var(--line);
  background: var(--white);
  padding: 18px 22px;
}
.case summary {
  font-weight: 700;
  min-height: 30px;
}
.case p {
  color: var(--muted);
}
.sources-section {
  scroll-margin-top: 90px;
}
.sources {
  padding-left: 30px;
}
.sources li {
  margin: 18px 0;
  font-size: 0.9rem;
  overflow-wrap: anywhere;
  scroll-margin-top: 100px;
}
.sources li:target {
  background: var(--wash);
  outline: 4px solid var(--wash);
}
.closing-card {
  margin-top: 40px;
  padding: 30px;
  border: 1px solid var(--line);
  background: var(--white);
}
.closing-card h3 {
  font-size: clamp(1.7rem, 3vw, 2.6rem);
  margin: 8px 0;
}
.glossary {
  display: grid;
  grid-template-columns: 130px 1fr;
  gap: 10px 20px;
}
.glossary dt {
  font-weight: 800;
}
.glossary dd {
  margin: 0;
}
.end {
  border-top: 1px solid var(--line);
  padding-top: 24px;
  padding-bottom: 40px;
  font-size: 0.8rem;
  color: var(--muted);
}
.contact-section {
  padding: clamp(56px, 8vw, 96px) 0;
  scroll-margin-top: 90px;
  border-top: 1px solid var(--line);
}
.contact-heading {
  max-width: 760px;
  margin: 0 auto 30px;
  text-align: center;
}
.contact-heading h2 {
  margin: 6px 0 10px;
}
.contact-heading > p:last-child {
  margin: 0 auto;
  color: var(--muted);
}
.inser-stage {
  display: flex;
  justify-content: center;
}
.inser-card {
  width: min(100%, 460px);
  position: relative;
  overflow: hidden;
  padding: clamp(30px, 6vw, 42px) clamp(22px, 5vw, 34px) 26px;
  border: 1px solid #36575b;
  border-radius: 28px;
  background:
    radial-gradient(circle at 50% -10%, #176b6c 0, transparent 38%),
    linear-gradient(165deg, #17393b 0%, #0b272b 58%, #081e24 100%);
  box-shadow: 0 22px 55px #102b3530;
  color: #fff;
  text-align: center;
}
.inser-pulse {
  position: absolute;
  inset: 0 0 auto;
  height: 64px;
  opacity: 0.55;
  pointer-events: none;
}
.inser-pulse svg {
  width: 200%;
  height: 100%;
  animation: inser-slide 9s linear infinite;
}
.inser-pulse path {
  fill: none;
  stroke: #79e1cf;
  stroke-width: 1.6;
}
@keyframes inser-slide {
  to {
    transform: translateX(-50%);
  }
}
.inser-emblem {
  width: 92px;
  height: 92px;
  margin: 14px auto 14px;
  display: grid;
  place-items: center;
  border: 1px solid #7de4d0aa;
  border-radius: 50%;
  background: #ffffff0c;
  box-shadow: 0 0 0 10px #76ddca0c;
}
.inser-emblem svg {
  width: 54px;
  fill: #50d3bd1f;
  stroke: #79e1cf;
  stroke-linecap: round;
  stroke-linejoin: round;
  stroke-width: 2.2;
}
.inser-kicker {
  margin: 0;
  color: #a9c6c5;
  font-size: 0.69rem;
  font-weight: 800;
  letter-spacing: 0.16em;
  text-transform: uppercase;
}
.inser-card h3 {
  margin: 6px 0 0;
  color: #fff;
  font-size: clamp(1.8rem, 7vw, 2.15rem);
  letter-spacing: -0.03em;
}
.inser-card h3 em {
  color: #8ce3cf;
  font-style: normal;
}
.inser-role {
  margin: 8px 0 0;
  color: #bdd1d0;
  font-size: 0.86rem;
  line-height: 1.5;
}
.inser-role strong {
  color: #fff;
}
.inser-chips {
  display: flex;
  flex-wrap: wrap;
  justify-content: center;
  gap: 7px;
  margin: 18px 0 4px;
}
.inser-chips span {
  padding: 5px 11px;
  border: 1px solid #527174;
  border-radius: 999px;
  color: #b8f1e4;
  background: #79e1cf0d;
  font-size: 0.69rem;
  font-weight: 700;
}
.inser-actions {
  display: grid;
  gap: 9px;
  margin-top: 22px;
}
.inser-link {
  display: grid;
  grid-template-columns: 44px minmax(0, 1fr) auto;
  align-items: center;
  gap: 13px;
  padding: 12px 14px;
  border: 1px solid #ffffff17;
  border-radius: 15px;
  background: #ffffff0a;
  color: #fff;
  text-align: left;
  text-decoration: none;
}
.inser-link:hover {
  background: #ffffff13;
  transform: translateY(-1px);
}
.inser-link.featured {
  border-color: transparent;
  background: linear-gradient(135deg, #087d7a, #0a968c);
}
.inser-icon {
  width: 44px;
  height: 40px;
  display: grid;
  place-items: center;
  border-radius: 11px;
  background: #ffffff16;
  font-size: 0.62rem;
  font-weight: 900;
  letter-spacing: 0.03em;
}
.inser-link b,
.inser-link small {
  display: block;
}
.inser-link b {
  font-size: 0.84rem;
}
.inser-link small {
  color: #a9c0bf;
  font-size: 0.7rem;
  overflow-wrap: anywhere;
}
.inser-link.featured small {
  color: #e3f8f3;
}
.inser-card-actions {
  display: flex;
  gap: 9px;
  margin-top: 17px;
}
.inser-card-actions button {
  flex: 1;
  min-height: 45px;
  padding: 8px;
  border: 1px solid #ffffff29;
  border-radius: 12px;
  background: transparent;
  color: #fff;
  font-size: 0.76rem;
  font-weight: 800;
}
.inser-card-actions button:hover {
  border-color: #79e1cf;
  background: #79e1cf0d;
}
.inser-feedback {
  min-height: 1.4em;
  margin: 8px 0 0;
  color: #b8f1e4;
  font-size: 0.72rem;
}
.inser-signature {
  margin: 8px 0 0;
  color: #91aaa9;
  font-size: 0.61rem;
  letter-spacing: 0.04em;
}
.inser-signature a {
  color: #8ce3cf;
}
.back-to-top {
  position: fixed;
  z-index: 18;
  right: 18px;
  bottom: 18px;
  width: 48px;
  height: 48px;
  border: 0;
  border-radius: 50%;
  background: #102b35;
  color: white;
  font-size: 1.4rem;
  box-shadow: 0 6px 18px #0003;
}
.back-to-top[hidden] {
  display: none;
}
.image-dialog {
  width: min(1100px, 94vw);
  max-width: none;
  padding: 44px 12px 12px;
  border: 1px solid var(--line);
  background: var(--paper);
  color: var(--ink);
}
.image-dialog::backdrop {
  background: #001014dc;
}
.image-dialog img {
  display: block;
  max-width: 100%;
  max-height: 82vh;
  margin: auto;
}
.image-dialog-close {
  position: absolute;
  right: 12px;
  top: 8px;
  border: 1px solid var(--line);
  background: var(--white);
  color: var(--ink);
  padding: 5px 10px;
  border-radius: 4px;
}
:root[data-theme="contrast"] .warning {
  background: #3a2b13;
  color: #ffe8be;
}
:root[data-theme="contrast"] .pediatric {
  background: #102f45;
  color: #d9efff;
}
@media (max-width: 800px) {
  .topbar {
    padding: 10px 16px;
    display: block;
  }
  .topbar > .brand {
    display: inline-block;
    margin-bottom: 8px;
  }
  .topbar nav {
    width: 100%;
    padding-bottom: 4px;
    padding-right: 4px;
  }
  .top-actions {
    position: absolute;
    right: 16px;
    top: 8px;
  }
  .print,
  .theme {
    font-size: 0.67rem;
    min-height: 32px;
    padding: 4px 7px;
  }
  main,
  footer {
    padding-left: 18px;
    padding-right: 18px;
  }
  .hero {
    padding-top: 38px;
  }
  .grid {
    grid-template-columns: 1fr;
    gap: 4px;
  }
  .fio2-card,
  .fio2-grid {
    grid-template-columns: 1fr;
  }
  .index ol {
    columns: 2;
  }
  .index-search {
    grid-template-columns: 1fr;
    gap: 6px;
  }
  .checklist {
    grid-template-columns: 1fr;
  }
  .chapter {
    scroll-margin-top: 130px;
  }
  .chapter-heading {
    grid-template-columns: 30px 1fr;
    gap: 8px;
  }
  .note {
    padding: 16px;
  }
  .cover img {
    aspect-ratio: auto;
  }
}
@media (max-width: 480px) {
  :root {
    font-size: 16px;
  }
  .topbar nav {
    margin-top: 2px;
  }
  .top-actions {
    position: static;
    margin: 6px 0 2px;
  }
  .topbar > .brand {
    margin-bottom: 2px;
  }
  .index {
    padding: 18px;
  }
  .index ol {
    columns: 1;
  }
  .glossary {
    grid-template-columns: 1fr;
    gap: 4px;
  }
  .glossary dd {
    margin-bottom: 12px;
  }
  .hero h1 {
    font-size: 2.65rem;
  }
  .topbar nav a {
    padding: 7px 10px;
  }
  .back-to-top {
    width: 44px;
    height: 44px;
    right: 12px;
    bottom: 12px;
  }
  .contact-heading {
    text-align: left;
  }
  .inser-card {
    border-radius: 20px;
    padding-inline: 16px;
  }
  .inser-link {
    grid-template-columns: 40px minmax(0, 1fr) auto;
    gap: 10px;
    padding-inline: 11px;
  }
  .inser-icon {
    width: 40px;
  }
}
@media (prefers-reduced-motion: no-preference) {
  html {
    scroll-behavior: smooth;
  }
  .back-to-top {
    transition:
      opacity 0.2s,
      transform 0.2s;
  }
  .topbar nav a {
    transition:
      background-color 0.2s,
      color 0.2s;
  }
}
@media (prefers-reduced-motion: reduce) {
  .inser-pulse svg {
    animation: none;
  }
}
@media print {
  .topbar,
  .actions,
  .skip,
  .index,
  .print,
  .theme,
  .reading-progress,
  .back-to-top,
  .image-dialog {
    display: none !important;
  }
  :root,
  :root[data-theme="contrast"] {
    --ink: #111;
    --muted: #444;
    --paper: #fff;
    --line: #bbb;
    --wash: #f3f3f3;
    --white: #fff;
    background: white;
    color: #111;
    font-size: 10pt;
    color-scheme: light;
  }
  main,
  footer {
    max-width: none;
    padding: 0;
  }
  .hero {
    padding-top: 0;
  }
  .hero h1 {
    font-size: 40pt;
  }
  .chapter {
    padding: 24px 0;
    break-before: page;
  }
  h2 {
    font-size: 25pt;
  }
  figure {
    break-inside: avoid;
    max-width: 100%;
  }
  figure img {
    max-height: 170mm;
    object-fit: contain;
  }
  .table-wrap {
    overflow: visible;
  }
  table {
    min-width: 0;
    font-size: 9pt;
  }
  .grid {
    display: block;
  }
  .checklist {
    display: block;
  }
  .checklist label {
    break-inside: avoid;
  }
  .sources li {
    font-size: 9pt;
  }
  a {
    color: #164c53;
  }
  .note {
    break-inside: avoid;
  }
}